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Tdark
PCYOX1L
Prenylcysteine oxidase-like

Protein Summary
Description
Probable oxidoreductase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000274569
  • ENSP00000274569
  • ENSG00000145882
  • ENST00000505669
  • ENSP00000427166
  • ENST00000511945
  • ENSP00000426091
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.73
histone modification site profile
0.7
cell type or tissue
0.69
tissue
0.56
transcription factor binding site profile
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (120)
SCGB2A1
Tbio
Novelty:  0.01902973
p_int:  0.999997965
p_ni:  0.000002035
Data Source:  BioPlex
PATE1
Tbio
Novelty:  0.0705075
p_int:  0.999949829
p_ni:  0.000050159
p_wrong:  1.2e-8
Score:  0.177
Data Source:  BioPlex,STRINGDB
LACRT
Tbio
Novelty:  0.03333799
p_int:  0.99973061
p_ni:  0.00026939
Score:  0.181
Data Source:  BioPlex,STRINGDB
LYZL2
Tdark
Family:  Enzyme
Novelty:  0.50542161
p_int:  0.997588425
p_ni:  0.002411556
p_wrong:  1.8e-8
Data Source:  BioPlex
IFNA21
Tbio
Novelty:  0.00581034
p_int:  0.997474242
p_ni:  0.00252574
p_wrong:  1.8e-8
Score:  0.177
Data Source:  BioPlex,STRINGDB
CD1B
Tbio
Novelty:  0.00102701
p_int:  0.994270414
p_ni:  0.005637062
p_wrong:  0.000092524
Data Source:  BioPlex
RLN2
Tbio
Novelty:  0.00743118
p_int:  0.993180308
p_ni:  0.006815291
p_wrong:  0.000004401
Data Source:  BioPlex
ITGA9
Tbio
Novelty:  0.01488635
p_int:  0.987162391
p_ni:  0.012834787
p_wrong:  0.000002822
Score:  0.189
Data Source:  BioPlex,STRINGDB
CLU
Tbio
Novelty:  0.00054776
p_int:  0.971192126
p_ni:  0.028804935
p_wrong:  0.000002939
Score:  0.915
Data Source:  BioPlex,STRINGDB
RLN1
Tbio
Novelty:  0.03992636
p_int:  0.900125498
p_ni:  0.035882319
p_wrong:  0.063992183
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Hemostasis (R-HSA-109582)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Hemostasis
Reactome
Platelet activation, signaling and aggregation
Reactome
Platelet degranulation
Reactome
Response to elevated platelet cytosolic Ca2+
Name
Explore in Pharos
Explore in Source
Hemostasis
Platelet activation, signaling and aggregation
Platelet degranulation
Response to elevated platelet cytosolic Ca2+
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
1
4
82.5
forced expiratory volume
1
1
1
62.1
mean platelet volume
1
1
1
50.6
vital capacity
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
4
82.5
forced expiratory volume
1
62.1
mean platelet volume
1
50.6
vital capacity
1
33.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
prenylcysteine oxidase 1 like
VGNC:4122
741792
Macaque
prenylcysteine oxidase 1 like
710587
Mouse
MGI:3606062
240334
Rat
RGD:1563290
307396
Dog
prenylcysteine oxidase 1 like
VGNC:44328
489194
Species
Name
OMA
EggNOG
Inparanoid
Chimp
prenylcysteine oxidase 1 like
Macaque
prenylcysteine oxidase 1 like
Mouse
Rat
Dog
prenylcysteine oxidase 1 like
Publication Statistics
PubMed Score 0.47
PubMed score by year
PubTator Score 0.57
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title