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Tbio
PCTP
Phosphatidylcholine transfer protein

Protein Summary
Description
Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000268896
  • ENSP00000268896
  • ENSG00000141179
  • ENST00000325214
  • ENSP00000325181

Symbol
  • STARD2
  • PC-TP
  • STARD2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.81
transcription factor perturbation
0.8
metabolite
0.79
interacting protein
0.71
tissue sample
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 151.31   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 194   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 151.31   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 194   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
VAPA
Tbio
Novelty:  0.00169209
p_int:  0.76897435
p_ni:  0.23102565
Score:  0.264
Data Source:  BioPlex,STRINGDB
ACOT13
Tbio
Family:  Enzyme
Novelty:  0.04119879
Score:  0.897
Data Source:  STRINGDB
STARD3
Tbio
Novelty:  0.01540936
Score:  0.808
Data Source:  STRINGDB
SLC38A5
Tbio
Family:  Transporter
Novelty:  0.0202197
Score:  0.804
Data Source:  STRINGDB
STARD6
Tbio
Novelty:  0.08085975
Score:  0.8
Data Source:  STRINGDB
STARD4
Tbio
Novelty:  0.05932371
Score:  0.8
Data Source:  STRINGDB
STARD5
Tbio
Novelty:  0.09052028
Score:  0.8
Data Source:  STRINGDB
PAX3
Tbio
Family:  TF
Novelty:  0.00140464
Score:  0.724
Data Source:  STRINGDB
ACOT12
Tbio
Family:  Enzyme
Novelty:  0.04464523
Score:  0.705
Data Source:  STRINGDB
COL4A3BP
Tbio
Novelty:  0.00357203
Score:  0.705
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Fatty acid metabolism (R-HSA-8978868)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Fatty acid metabolism
Reactome
Glycerophospholipid biosynthesis
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Mitochondrial Fatty Acid Beta-Oxidation
Name
Explore in Pharos
Explore in Source
Fatty acid metabolism
Glycerophospholipid biosynthesis
Metabolism
Metabolism of lipids
Mitochondrial Fatty Acid Beta-Oxidation
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
2
2
2
70.5
appendicular lean mass
1
2
2
67
brain measurement
1
1
0
7.1
45
brain volume measurement
1
1
1
40.8
cortical thickness
1
1
0
6.5
36
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
2
70.5
appendicular lean mass
2
67
brain measurement
0
7.1
45
brain volume measurement
1
40.8
cortical thickness
0
6.5
36
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
phosphatidylcholine transfer protein
VGNC:9503
455143
Macaque
phosphatidylcholine transfer protein
707128
Mouse
MGI:107375
18559
Rat
RGD:3276
29510
Dog
phosphatidylcholine transfer protein
VGNC:44326
480563
Species
Name
OMA
EggNOG
Inparanoid
Chimp
phosphatidylcholine transfer protein
Macaque
phosphatidylcholine transfer protein
Mouse
Rat
Dog
phosphatidylcholine transfer protein
Publication Statistics
PubMed Score 151.31
PubMed score by year
PubTator Score 19.44
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title