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Tdark
PCNX3
Pecanex-like protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355703
  • ENSP00000347931
  • ENSG00000197136

Symbol
  • PCNXL3
  • PCNXL3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.96   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.96   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (55)
TM2D1
Tdark
Novelty:  0.1760181
p_int:  0.999982917
p_ni:  0.000017076
p_wrong:  7e-9
Data Source:  BioPlex
FAM189A2
Tdark
Novelty:  0.41335428
p_int:  0.999415175
p_ni:  0.000584825
p_wrong:  1e-9
Data Source:  BioPlex
TMEM31
Tdark
Novelty:  0.65381391
p_int:  0.999188675
p_ni:  0.000811324
p_wrong:  1e-9
Data Source:  BioPlex
ZNRF4
Tbio
Novelty:  0.16505328
p_int:  0.997680565
p_ni:  0.002319435
Data Source:  BioPlex
RXFP1
Tchem
Family:  GPCR
Novelty:  0.00580827
p_int:  0.9926367
p_ni:  0.007363291
p_wrong:  9e-9
Data Source:  BioPlex
RNF185
Tbio
Family:  Enzyme
Novelty:  0.23911257
p_int:  0.991667964
p_ni:  0.008332036
Score:  0.175
Data Source:  BioPlex,STRINGDB
SLC13A2
Tbio
Family:  Transporter
Novelty:  0.01020451
p_int:  0.984708414
p_ni:  0.015291585
Score:  0.185
Data Source:  BioPlex,STRINGDB
SLC4A8
Tbio
Family:  Transporter
Novelty:  0.01606111
p_int:  0.982407313
p_ni:  0.017592681
p_wrong:  6e-9
Data Source:  BioPlex
CHRNB1
Tclin
Family:  IC
Novelty:  0.04777051
p_int:  0.975529105
p_ni:  0.024443298
p_wrong:  0.000027597
Data Source:  BioPlex
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.960657186
p_ni:  0.039342814
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (48)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
5
97.8
heel bone mineral density
3
6
8
95.7
urate measurement
3
4
4
94
mean platelet volume
3
2
3
93.2
glomerular filtration rate
2
3
3
91.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
5
97.8
heel bone mineral density
8
95.7
urate measurement
4
94
mean platelet volume
3
93.2
glomerular filtration rate
3
91.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
pecanex homolog 3
VGNC:6697
100612133
Mouse
MGI:1861733
104401
Rat
RGD:1305529
309167
Dog
pecanex homolog 3
VGNC:44314
483731
Horse
pecanex homolog 3
VGNC:21210
100057407
Species
Name
OMA
EggNOG
Inparanoid
Chimp
pecanex homolog 3
Mouse
Rat
Dog
pecanex homolog 3
Horse
pecanex homolog 3
Publication Statistics
PubMed Score 0.96
PubMed score by year
PubTator Score 0.09
PubTator score by year
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Related Publications
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PMID
Year
Title