Tbio PCIF1 Phosphorylated CTD-interacting factor 1

Protein Summary

Description

May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit.

Uniprot Accession IDs

• Q9H4Z3
• E1P5P1
• Q54AB9
• Q9NT85

Gene Name

• PCIF1

Ensembl ID

• ENST00000372409
• ENSP00000361486
• ENSG00000100982

Symbol

• C20orf67
• CAPAM
• hCAPAM
• hPCIF1
• C20orf67
• PPP1R121

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.91
histone modification site profile	0.81
transcription factor perturbation	0.8
transcription factor	0.7
tissue	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.11   (req: < 5)

Gene RIFs: 16   (req: <= 3)

Antibodies: 69   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.11   (req: >= 5)

Gene RIFs: 16   (req: > 3)

Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0