Tdark PCED1B PC-esterase domain-containing protein 1B

Protein Summary

Description

This gene encodes a protein that belongs to the GDSL/SGNH-like acyl-esterase family. Members of this family are hydrolases thought to function in modification of biopolymers on the cell surface. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Uniprot Accession IDs

• Q96HM7
• Q96B20

Gene Name

• PCED1B

Ensembl ID

• ENST00000432328
• ENSP00000396040
• ENSG00000179715
• ENST00000546455
• ENSP00000446688

Symbol

• FAM113B
• FAM113B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.84
tissue sample	0.65
transcription factor	0.56
cell type or tissue	0.54
gene perturbation	0.53

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.21   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 23   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.21   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0