Tbio PCDH7 Protocadherin-7

Protein Summary

Description

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O60245
• O60246
• O60247
• Q4W5C4

Gene Name

• PCDH7

Ensembl ID

• ENST00000361762
• ENSP00000355243
• ENSG00000169851
• ENST00000543491
• ENSP00000441802

Symbol

• BHPCDH
• BHPCDH
• BH-Pcdh
• PPP1R120

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	1
PubMedID	0.9
microRNA	0.8
protein domain	0.73
disease	0.72

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.29   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 298   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.29   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 298   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0