Protein Summary
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
- ENST00000361762
- ENSP00000355243
- ENSG00000169851
- ENST00000543491
- ENSP00000441802
- BHPCDH
- BHPCDH
- BH-Pcdh
- PPP1R120
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 1 | ||
PubMedID | 0.9 | ||
microRNA | 0.8 | ||
protein domain | 0.73 | ||
disease | 0.72 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.91 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 298 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.91 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 298 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (47)
PCDHGB1
Novelty: 0.60440805
p_int: 0.998996752
p_ni: 0.001003248
Score: 0.177
Data Source: BioPlex,STRINGDB
C2orf48
Novelty: 1
p_int: 0.998324915
p_ni: 0.001675085
Score: 0.638
Data Source: BioPlex,STRINGDB
NXPH2
Novelty: 0.65790631
p_int: 0.978281926
p_ni: 0.021718074
Score: 0.333
Data Source: BioPlex,STRINGDB
FCGR1A
Novelty: 0.00073204
p_int: 0.96363898
p_ni: 0.03636102
Score: 0.795
Data Source: BioPlex,STRINGDB
PCDH20
Novelty: 0.07862843
p_int: 0.959677876
p_ni: 0.040322124
Score: 0.713
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (6)
Reactome (4)
PathwayCommons (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Hemostasis | ||||
Reactome | Platelet activation, signaling and aggregation | ||||
Reactome | Platelet degranulation | ||||
Reactome | Response to elevated platelet cytosolic Ca2+ | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Hemostasis | ||||
Platelet activation, signaling and aggregation | ||||
Platelet degranulation | ||||
Response to elevated platelet cytosolic Ca2+ | ||||
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (1)
Components (3)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (15)
Items per page:
1 – 5 of 15
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
risk-taking behaviour | 2 | 5 | 5 | 83.1 | |||||
smoking status measurement | 2 | 1 | 2 | 69.5 | |||||
risky sexual behaviour measurement | 1 | 2 | 2 | 65.7 | |||||
comparative body size at age 10, self-reported | 1 | 1 | 1 | 65.6 | |||||
smoking initiation | 1 | 1 | 1 | 54.4 | |||||
Items per page:
1 – 5 of 15
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
risk-taking behaviour | 5 | 83.1 | |||||
smoking status measurement | 2 | 69.5 | |||||
risky sexual behaviour measurement | 2 | 65.7 | |||||
comparative body size at age 10, self-reported | 1 | 65.6 | |||||
smoking initiation | 1 | 54.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | protocadherin 7 | VGNC:660 | 461157 | |||||
Macaque | protocadherin 7 | 696011 | ||||||
Mouse | MGI:1860487 | 54216 | ||||||
Rat | RGD:1303209 | 360942 | ||||||
Dog | protocadherin 7 | VGNC:53195 | 488843 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | protocadherin 7 | |||||
Macaque | protocadherin 7 | |||||
Mouse | ||||||
Rat | ||||||
Dog | protocadherin 7 | |||||
Publication Statistics
PubMed Score 35.91
PubMed score by year
PubTator Score 12.17
PubTator score by year
Related Publications
Text Mined References (26)
GeneRif Annotations (9)
Items per page:
0 of 0
PMID | Year | Title |
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