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Tbio
PCDH20
Protocadherin-20

Protein Summary
Description
Potential calcium-dependent cell-adhesion protein. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000409204
  • ENSP00000387250
  • ENSG00000280165

Symbol
  • PCDH13
  • PCDH13
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.78
kinase perturbation
0.66
microRNA
0.63
cell type or tissue
0.61
cell line
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.83   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 31   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.83   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (67)
CCDC51
Tdark
Novelty:  1.19203634
p_int:  0.999996189
p_ni:  0.000003811
Data Source:  BioPlex
SUPT7L
Tdark
Novelty:  0.20661559
p_int:  0.999913381
p_ni:  0.000086583
p_wrong:  3.6e-8
Data Source:  BioPlex
LTBP1
Tbio
Novelty:  0.00958396
p_int:  0.999492223
p_ni:  0.000507777
Data Source:  BioPlex
PCDH17
Tbio
Novelty:  0.03341603
p_int:  0.999220516
p_ni:  0.000775488
p_wrong:  0.000003996
Score:  0.424
Data Source:  BioPlex,STRINGDB
CBX6
Tchem
Family:  Epigenetic
Novelty:  0.08868575
p_int:  0.996994044
p_ni:  0.003005949
p_wrong:  7e-9
Data Source:  BioPlex
TAF5L
Tbio
Family:  Enzyme
Novelty:  0.29525944
p_int:  0.996284655
p_ni:  0.003715338
p_wrong:  8e-9
Data Source:  BioPlex
MAP3K7
Tchem
Family:  Kinase
Novelty:  0.00540177
p_int:  0.996164796
p_ni:  0.003835202
p_wrong:  1e-9
Data Source:  BioPlex
CELSR3
Tbio
Family:  GPCR
Novelty:  0.02705624
p_int:  0.995353433
p_ni:  0.004646566
p_wrong:  1e-9
Score:  0.551
Data Source:  BioPlex,STRINGDB
TAF9B
Tbio
Novelty:  0.0285313
p_int:  0.992324277
p_ni:  0.007671256
p_wrong:  0.000004467
Data Source:  BioPlex
RPL23
Tbio
Novelty:  0.02741113
p_int:  0.991879965
p_ni:  0.008120035
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
PathwayCommons: panther
Cadherin signaling pathway
PathwayCommons: panther
Wnt signaling pathway
Name
Explore in Pharos
Explore in Source
Cadherin signaling pathway
Wnt signaling pathway
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
protocadherin 20
VGNC:53393
452749
Macaque
protocadherin 20
696607
Mouse
MGI:2443376
219257
Rat
RGD:1306297
306081
Dog
protocadherin 20
100686939
Species
Name
OMA
EggNOG
Inparanoid
Chimp
protocadherin 20
Macaque
protocadherin 20
Mouse
Rat
Dog
protocadherin 20
Publication Statistics
PubMed Score 16.83
PubMed score by year
PubTator Score 8.28
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title