PBX1
Pre-B-cell leukemia transcription factor 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 1 | ||
kinase perturbation | 0.99 | ||
PubMedID | 0.95 | ||
virus perturbation | 0.92 | ||
biological process | 0.9 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of HOX genes during differentiation | ||||
Reactome | Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Reactome | Developmental Biology | ||||
Reactome | NOTCH3 Intracellular Domain Regulates Transcription | ||||
Reactome | Signal Transduction | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of HOX genes during differentiation | ||||
Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Developmental Biology | ||||
NOTCH3 Intracellular Domain Regulates Transcription | ||||
Signal Transduction | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Non-traceable Author Statement (NAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
balding measurement | 1 | 3 | 3 | 89.7 | |||||
viral load | 1 | 1 | 1 | 73.9 | |||||
mean platelet volume | 2 | 1 | 2 | 72.9 | |||||
BMI-adjusted waist-hip ratio | 2 | 2 | 2 | 63.6 | |||||
waist circumference | 1 | 1 | 1 | 50.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
balding measurement | 3 | 89.7 | |||||
viral load | 1 | 73.9 | |||||
mean platelet volume | 2 | 72.9 | |||||
BMI-adjusted waist-hip ratio | 2 | 63.6 | |||||
waist circumference | 1 | 50.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | PBX homeobox 1 | VGNC:11604 | 457474 | |||||
Macaque | PBX homeobox 1 | 694416 | ||||||
Mouse | MGI:97495 | 18514 | ||||||
Rat | RGD:1308213 | 304947 | ||||||
Dog | PBX homeobox 1 | VGNC:44286 | 488669 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | PBX homeobox 1 | |||||
Macaque | PBX homeobox 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | PBX homeobox 1 | |||||
PMID | Year | Title |
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