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Tdark
PATE4
Prostate and testis expressed protein 4

Protein Summary
Description
May modulate the function of nicotinic acetylcholine receptors. May enhance sperm motility.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000457514
  • ENSP00000411439
  • ENSG00000237353

Symbol
  • PATE-B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.99
cellular component
0.44
cell line
0.37
biological term
0.33
tissue sample
0.33


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.09   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 19   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.09   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
PATE2
Tdark
Novelty:  0.33130253
Score:  0.792
Data Source:  STRINGDB
PATE3
Tdark
Novelty:  0.64960844
Score:  0.79
Data Source:  STRINGDB
SLURP1
Tbio
Novelty:  0.00710864
Score:  0.664
Data Source:  STRINGDB
PATE1
Tbio
Novelty:  0.0705075
Score:  0.591
Data Source:  STRINGDB
LY6L
Tdark
Novelty:  14.46115589
Score:  0.588
Data Source:  STRINGDB
ACRV1
Tbio
Novelty:  0.00291978
Score:  0.587
Data Source:  STRINGDB
PINLYP
Tdark
Family:  Enzyme
Novelty:  3.21624712
Score:  0.56
Data Source:  STRINGDB
EQTN
Tdark
Novelty:  0.0547955
Score:  0.557
Data Source:  STRINGDB
SEMG1
Tbio
Novelty:  0.0161449
Score:  0.547
Data Source:  STRINGDB
SEMG2
Tbio
Novelty:  0.06325799
Score:  0.544
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
1
1
1
21.5
mean platelet volume
1
1
1
12.9
mean corpuscular hemoglobin concentration
1
1
1
11.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
1
21.5
mean platelet volume
1
12.9
mean corpuscular hemoglobin concentration
1
11.5
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
prostate and testis expressed 4
740163
Mouse
MGI:1930790
56872
Rat
RGD:1311172
363041
Species
Name
OMA
EggNOG
Inparanoid
Chimp
prostate and testis expressed 4
Mouse
Rat
Publication Statistics
PubMed Score 3.09
PubMed score by year
PubTator Score 0.46
PubTator score by year
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Related Publications
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PMID
Year
Title