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Tbio
PARVG
Gamma-parvin

Protein Summary
Description
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Members of the parvin family, including PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM, Aug 2004]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356909
  • ENSP00000349378
  • ENSG00000138964
  • ENST00000415224
  • ENSP00000416761
  • ENST00000422871
  • ENSP00000391453
  • ENST00000444313
  • ENSP00000391583
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor
0.64
tissue sample
0.62
cell type or tissue
0.53
tissue
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.88   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.88   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (102)
ILK
Tchem
Family:  Kinase
Novelty:  0.00147344
p_int:  0.999998993
p_ni:  0.000001007
Score:  0.998
Data Source:  BioPlex,STRINGDB
RSU1
Tbio
Novelty:  0.01645054
p_int:  0.999997561
p_ni:  0.000002439
Score:  0.902
Data Source:  BioPlex,STRINGDB
LIMS1
Tbio
Novelty:  0.00648304
p_int:  0.999962246
p_ni:  0.000037754
Score:  0.951
Data Source:  BioPlex,STRINGDB
POLK
Tbio
Family:  Enzyme
Novelty:  0.01378154
p_int:  0.999616656
p_ni:  0.000198971
p_wrong:  0.000184373
Score:  0.559
Data Source:  BioPlex,STRINGDB
ASGR2
Tbio
Novelty:  0.14671716
p_int:  0.999534923
p_ni:  0.000465067
p_wrong:  1e-8
Score:  0.255
Data Source:  BioPlex,STRINGDB
SULT4A1
Tbio
Family:  Enzyme
Novelty:  0.02455678
p_int:  0.99901204
p_ni:  0.000987804
p_wrong:  1.57e-7
Score:  0.197
Data Source:  BioPlex,STRINGDB
AARSD1
Tdark
Novelty:  0.75372406
p_int:  0.861443379
p_ni:  0.138468506
p_wrong:  0.000088115
Score:  0.219
Data Source:  BioPlex,STRINGDB
ARHGEF6
Tbio
Novelty:  0.02162737
Score:  0.957
Data Source:  STRINGDB
PXN
Tbio
Novelty:  0.00082031
Score:  0.937
Data Source:  STRINGDB
PARVB
Tbio
Novelty:  0.03825772
Score:  0.817
Data Source:  STRINGDB
Nearest Tclin Targets (15)
Explore Nearest Tclin Targets
1 – 5 of 14
PIK3CA
Tclin
Family:  Kinase
KEGG Distance:  3
Common Pathways:  1
PDGFRA
Tclin
Family:  Kinase
KEGG Distance:  3
Common Pathways:  1
PIK3CD
Tclin
Family:  Kinase
KEGG Distance:  3
Common Pathways:  1
ITGB3
Tclin
Family:  Other
KEGG Distance:  3
Common Pathways:  1
FLT4
Tclin
Family:  Kinase
KEGG Distance:  3
Common Pathways:  1
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
parental longevity
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
parental longevity
1
17.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
parvin gamma
VGNC:6024
458899
Macaque
parvin gamma
712624
Mouse
MGI:2158329
64099
Rat
RGD:1597417
689069
Dog
parvin gamma
VGNC:44268
481214
Species
Name
OMA
EggNOG
Inparanoid
Chimp
parvin gamma
Macaque
parvin gamma
Mouse
Rat
Dog
parvin gamma
Publication Statistics
PubMed Score 9.88
PubMed score by year
PubTator Score 5.07
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title