PARN
Poly(A)-specific ribonuclease PARN
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.94 | ||
disease perturbation | 0.93 | ||
virus perturbation | 0.92 | ||
transcription factor binding site profile | 0.85 | ||
co-expressed gene | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ATF4 activates genes in response to endoplasmic reticulum stress | ||||
Reactome | Deadenylation of mRNA | ||||
Reactome | Deadenylation-dependent mRNA decay | ||||
Reactome | KSRP (KHSRP) binds and destabilizes mRNA | ||||
Reactome | Metabolism of RNA | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ATF4 activates genes in response to endoplasmic reticulum stress | ||||
Deadenylation of mRNA | ||||
Deadenylation-dependent mRNA decay | ||||
KSRP (KHSRP) binds and destabilizes mRNA | ||||
Metabolism of RNA | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred by Curator (IC) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 1 | 1 | 55.2 | |||||
mathematical ability | 1 | 1 | 1 | 52 | |||||
1 | 1 | 0 | 2.2 | 38.8 | |||||
diastolic blood pressure | 1 | 1 | 1 | 5.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 55.2 | |||||
mathematical ability | 1 | 52 | |||||
0 | 2.2 | 38.8 | |||||
diastolic blood pressure | 1 | 5.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | poly(A)-specific ribonuclease | VGNC:13784 | 453936 | |||||
Macaque | poly(A)-specific ribonuclease | 712984 | ||||||
Mouse | MGI:1921358 | 74108 | ||||||
Rat | RGD:1565449 | 360464 | ||||||
Dog | poly(A)-specific ribonuclease | VGNC:53535 | 479839 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | poly(A)-specific ribonuclease | |||||
Macaque | poly(A)-specific ribonuclease | |||||
Mouse | ||||||
Rat | ||||||
Dog | poly(A)-specific ribonuclease | |||||
PMID | Year | Title |
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