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Tdark
PAQR4
Progestin and adipoQ receptor family member 4

Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.82   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 24   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.82   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
TIMM8A
Tbio
Family:  Enzyme
Novelty:  0.00954602
p_int:  0.999989749
p_ni:  9.8e-8
p_wrong:  0.000010153
Data Source:  BioPlex
FAM136A
Tdark
Novelty:  0.4050275
p_int:  0.999386004
p_ni:  7.3e-7
p_wrong:  0.000613266
Score:  0.202
Data Source:  BioPlex,STRINGDB
MYADML2
Tdark
Novelty:  1.43792271
Score:  0.812
Data Source:  STRINGDB
PAQR9
Tdark
Novelty:  0.39198507
Score:  0.722
Data Source:  STRINGDB
STX1B
Tbio
Novelty:  0.01171833
Score:  0.682
Data Source:  STRINGDB
PAQR6
Tbio
Novelty:  0.10793454
Score:  0.553
Data Source:  STRINGDB
PAQR7
Tbio
Novelty:  0.00870986
Score:  0.552
Data Source:  STRINGDB
RPL26L1
Tdark
Novelty:  0.75408617
Score:  0.544
Data Source:  STRINGDB
ASB2
Tbio
Novelty:  0.02852942
Score:  0.541
Data Source:  STRINGDB
KIAA1586
Tdark
Novelty:  2.30999532
Score:  0.536
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aspartate aminotransferase measurement
1
1
1
53.7
serum alanine aminotransferase measurement
1
1
1
17.2
balding measurement
1
1
1
13.1
sex hormone-binding globulin measurement
1
1
1
6.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aspartate aminotransferase measurement
1
53.7
serum alanine aminotransferase measurement
1
17.2
balding measurement
1
13.1
sex hormone-binding globulin measurement
1
6.6
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
progestin and adipoQ receptor family member 4
VGNC:9097
750171
Macaque
progestin and adipoQ receptor family member 4
699484
Mouse
MGI:1923748
76498
Rat
RGD:1309533
302967
Dog
progestin and adipoQ receptor family member 4
VGNC:44260
490051
Species
Name
OMA
EggNOG
Inparanoid
Chimp
progestin and adipoQ receptor family member 4
Macaque
progestin and adipoQ receptor family member 4
Mouse
Rat
Dog
progestin and adipoQ receptor family member 4
Publication Statistics
PubMed Score 5.82
PubMed score by year
PubTator Score 0.88
PubTator score by year
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Related Publications
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PMID
Year
Title