PAM
Peptidyl-glycine alpha-amidating monooxygenase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.99 | ||
transcription factor perturbation | 0.91 | ||
molecular function | 0.88 | ||
virus perturbation | 0.85 | ||
ligand (protein) perturbation | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
PathwayCommons: panther | Vasopressin synthesis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Vasopressin synthesis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
7 | 4 | 1 | 1.1 | 94 | |||||
balding measurement | 1 | 2 | 2 | 81 | |||||
appendicular lean mass | 3 | 1 | 3 | 65.6 | |||||
Drugs used in diabetes use measurement | 1 | 1 | 1 | 64.4 | |||||
sleep duration | 2 | 2 | 1 | 1 | 63 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
1 | 1.1 | 94 | |||||
balding measurement | 2 | 81 | |||||
appendicular lean mass | 3 | 65.6 | |||||
Drugs used in diabetes use measurement | 1 | 64.4 | |||||
sleep duration | 1 | 1 | 63 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | peptidylglycine alpha-amidating monooxygenase | VGNC:4116 | 461974 | |||||
Macaque | peptidylglycine alpha-amidating monooxygenase | 707733 | ||||||
Mouse | MGI:97475 | 18484 | ||||||
Rat | RGD:3252 | 25508 | ||||||
Dog | peptidylglycine alpha-amidating monooxygenase | VGNC:44250 | 479145 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | peptidylglycine alpha-amidating monooxygenase | |||||
Macaque | peptidylglycine alpha-amidating monooxygenase | |||||
Mouse | ||||||
Rat | ||||||
Dog | peptidylglycine alpha-amidating monooxygenase | |||||
PMID | Year | Title |
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