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Tdark
PABPC4L
Polyadenylate-binding protein 4-like

Protein Summary
Description
May bind RNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000421491
  • ENSP00000463233
  • ENSG00000254535
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.9
microRNA
0.68
gene perturbation
0.59
histone modification site profile
0.58
virus perturbation
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.53   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.53   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (51)
ELAVL2
Tbio
Novelty:  0.00370708
p_int:  0.999775595
p_ni:  0.000223279
p_wrong:  0.000001125
Score:  0.325
Data Source:  BioPlex,STRINGDB
LARP4B
Tbio
Novelty:  0.11363794
p_int:  0.999639642
p_ni:  0.000350983
p_wrong:  0.000009375
Score:  0.352
Data Source:  BioPlex,STRINGDB
DGCR8
Tbio
Novelty:  0.00271221
p_int:  0.999551498
p_ni:  0.000447388
p_wrong:  0.000001114
Data Source:  BioPlex
TRA2A
Tbio
Novelty:  0.04935993
p_int:  0.999438897
p_ni:  0.000559081
p_wrong:  0.000002021
Score:  0.309
Data Source:  BioPlex,STRINGDB
ZC3HAV1
Tbio
Novelty:  0.01357759
p_int:  0.999119189
p_ni:  0.000873608
p_wrong:  0.000007203
Score:  0.516
Data Source:  BioPlex,STRINGDB
GSPT2
Tchem
Family:  Enzyme
Novelty:  0.08140512
p_int:  0.9967952
p_ni:  0.001539545
p_wrong:  0.001665255
Score:  0.684
Data Source:  BioPlex,STRINGDB
H2AFX
Tbio
Novelty:  0.00048694
p_int:  0.992583385
p_ni:  0.006883085
p_wrong:  0.000533529
Score:  0.179
Data Source:  BioPlex,STRINGDB
NOP53
Tbio
Novelty:  0.00353077
p_int:  0.992395197
p_ni:  0.005347093
p_wrong:  0.002257709
Score:  0.157
Data Source:  BioPlex,STRINGDB
RPL23A
Tbio
Novelty:  0.02951947
p_int:  0.984070633
p_ni:  0.004014907
p_wrong:  0.011914459
Score:  0.237
Data Source:  BioPlex,STRINGDB
RNF151
Tdark
Novelty:  2.0077961
p_int:  0.981695702
p_ni:  0.001806765
p_wrong:  0.016497534
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
RNA degradation
KEGG
mRNA surveillance pathway
KEGG
RNA transport
Name
Explore in Pharos
Explore in Source
RNA degradation
mRNA surveillance pathway
RNA transport
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
birth weight
1
1
1
58.4
body height at birth
1
1
1
0.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
birth weight
1
58.4
body height at birth
1
0.3
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 1.53
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title