FOXO4
Forkhead box protein O4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.9 | ||
hub protein | 0.88 | ||
histone modification site profile | 0.78 | ||
biological term | 0.77 | ||
kinase | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | AKT phosphorylates targets in the nucleus | ||||
Reactome | Constitutive Signaling by AKT1 E17K in Cancer | ||||
Reactome | Deubiquitination | ||||
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
AKT phosphorylates targets in the nucleus | ||||
Constitutive Signaling by AKT1 E17K in Cancer | ||||
Deubiquitination | ||||
Disease | ||||
Diseases of signal transduction | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred by Curator (IC) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 2 | 3 | 94.6 | |||||
reticulocyte count | 2 | 1 | 2 | 86.6 | |||||
testosterone measurement | 1 | 1 | 1 | 12 | |||||
2 | 1 | 0 | 1 | 10.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 94.6 | |||||
reticulocyte count | 2 | 86.6 | |||||
testosterone measurement | 1 | 12 | |||||
0 | 1 | 10.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | forkhead box O4 | VGNC:1385 | 473659 | |||||
Macaque | forkhead box O4 | 698055 | ||||||
Mouse | MGI:1891915 | 54601 | ||||||
Rat | RGD:1561201 | 302415 | ||||||
Dog | forkhead box O4 | VGNC:40964 | 100855644 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | forkhead box O4 | |||||
Macaque | forkhead box O4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | forkhead box O4 | |||||
PMID | Year | Title |
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