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Tbio
RBM10
RNA-binding protein 10

Protein Summary
Description
May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins (PubMed:28431233). This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329236
  • ENSP00000328848
  • ENSG00000182872
  • ENST00000345781
  • ENSP00000329659
  • ENST00000377604
  • ENSP00000366829
  • ENST00000628161
  • ENSP00000486115

Symbol
  • DXS8237E
  • GPATC9
  • GPATCH9
  • KIAA0122
  • S1-1
  • TARPS
  • GPATC9
  • ZRANB5
  • GPATCH9
  • DXS8237E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
histone modification site profile
0.91
protein complex
0.88
protein domain
0.85
ligand (protein) perturbation
0.83


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.24   (req: < 5)
Gene RIFs: 25   (req: <= 3)
Antibodies: 182   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.24   (req: >= 5)
Gene RIFs: 25   (req: > 3)
Antibodies: 182   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
RNA binding motif protein 10
711791
Mouse
MGI:2384310
236732
Rat
RGD:631366
64510
Dog
RNA binding motif protein 10
VGNC:45404
480895
Horse
RNA binding motif protein 10
VGNC:22231
100051096
Species
Name
OMA
EggNOG
Inparanoid
Macaque
RNA binding motif protein 10
Mouse
Rat
Dog
RNA binding motif protein 10
Horse
RNA binding motif protein 10
Protein Structure (4 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P98175-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 4 of 4
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Protein-Protein Interactions (140)
1 – 10 of 140
HSD17B1
Tchem
Family: Enzyme
Novelty: 0.00313425
p_int: 0.900758183
p_ni: 0.099241817
Data Source: BioPlex
RBM17
Tbio
Novelty: 0.04840999
p_int: 0.774176849
p_ni: 0.225822964
p_wrong: 1.87e-7
Score: 0.583
Data Source: BioPlex,STRINGDB
CNIH2
Tbio
Novelty: 0.08676822
Score: 0.876
Data Source: STRINGDB
CACNG2
Tbio
Family: IC
Novelty: 0.00808502
Score: 0.86
Data Source: STRINGDB
U2AF2
Tbio
Novelty: 0.00590935
Score: 0.852
Data Source: STRINGDB
DLG4
Tchem
Novelty: 0.00057285
Score: 0.806
Data Source: STRINGDB
CNIH3
Tdark
Novelty: 0.22096987
Score: 0.804
Data Source: STRINGDB
UBA1
Tbio
Novelty: 0.00419724
Score: 0.796
Data Source: STRINGDB
GPKOW
Tbio
Novelty: 0.14830491
Score: 0.788
Data Source: STRINGDB
DHX15
Tbio
Family: Enzyme
Novelty: 0.0134377
Score: 0.788
Data Source: STRINGDB
Publication Statistics
PubMed Score  50.24

PubMed score by year
PubTator Score  35.47

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer