You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
RBM10
RNA-binding protein 10

Protein Summary
Description
May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins (PubMed:28431233). This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329236
  • ENSP00000328848
  • ENSG00000182872
  • ENST00000345781
  • ENSP00000329659
  • ENST00000377604
  • ENSP00000366829
  • ENST00000628161
  • ENSP00000486115

Symbol
  • DXS8237E
  • GPATC9
  • GPATCH9
  • KIAA0122
  • S1-1
  • TARPS
  • GPATC9
  • ZRANB5
  • GPATCH9
  • DXS8237E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
histone modification site profile
0.91
protein complex
0.88
protein domain
0.85
ligand (protein) perturbation
0.83


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.07   (req: < 5)
Gene RIFs: 45   (req: <= 3)
Antibodies: 182   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.07   (req: >= 5)
Gene RIFs: 45   (req: > 3)
Antibodies: 182   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0