Tbio FAM3A Protein FAM3A

Protein Summary

Description

May act as a defensin against invading fungal microorganisms. This gene encodes a cytokine-like protein. The expression of this gene may be regulated by peroxisome proliferator-activated receptor gamma, and the encoded protein may be involved in the regulation of glucose and lipid metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Accession IDs

• P98173
• A6QRH6
• B2RBI7
• B4DFI8
• D3DWX4
• Q5HY76
• Q96H51

Gene Name

• FAM3A

Ensembl ID

• ENST00000359889
• ENSP00000352955
• ENSG00000071889
• ENST00000369643
• ENSP00000358657
• ENST00000393572
• ENSP00000377202
• ENST00000419205
• ENSP00000393086
• ENST00000447601
• ENSP00000416146

Symbol

• 2-19
• 2.19
• DLD
• 2.19
• XAP-7
• DXS560S

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.9
virus perturbation	0.72
cell type or tissue	0.62
gene perturbation	0.53
tissue sample	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.51   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 134   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.51   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0