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Tbio
MUC5AC
Mucin-5AC

Protein Summary
Description
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000621226
  • ENSP00000485659
  • ENSG00000215182
  • ENST00000636567
  • ENSP00000490794
  • ENSG00000283158

Symbol
  • MUC5
  • TBM
  • leB
  • MUC5
  • mucin
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological term
0.98
gene perturbation
0.86
chemical
0.71
cell line
0.69
interacting protein
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1636.27   (req: < 5)
Gene RIFs: 332   (req: <= 3)
Antibodies: 912   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1636.27   (req: >= 5)
Gene RIFs: 332   (req: > 3)
Antibodies: 912   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0