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Tdark
SERF2
Small EDRK-rich factor 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000249786
  • ENSP00000249786
  • ENSG00000140264
  • ENST00000339624
  • ENSP00000339647
  • ENST00000381359
  • ENSP00000370764
  • ENST00000402131
  • ENSP00000386044
  • ENST00000403425
  • ENSP00000384300
  • ENST00000409614
  • ENSP00000386783
  • ENST00000409960
  • ENSP00000387187
  • ENST00000445816
  • ENSP00000400178

Symbol
  • FAM2C
  • FAM2C
  • 4F5REL
  • H4F5REL
  • HsT17089
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
virus perturbation
0.9
kinase perturbation
0.88
transcription factor perturbation
0.88
histone modification site profile
0.87


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.52   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.52   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (25)
1 – 10 of 25
HYPK
Tbio
Novelty:  0.085555
Score:  0.713
Data Source:  STRINGDB
MATR3
Tbio
Novelty:  0.01218438
Score:  0.65
Data Source:  STRINGDB
MFAP1
Tbio
Novelty:  0.15311456
Score:  0.625
Data Source:  STRINGDB
SERINC4
Tdark
Novelty:  0.97085689
Score:  0.543
Data Source:  STRINGDB
RPLP1
Tbio
Novelty:  0.01471148
Score:  0.528
Data Source:  STRINGDB
FUBP1
Tbio
Novelty:  0.01745195
Score:  0.503
Data Source:  STRINGDB
SCAF8
Tbio
Novelty:  0.1650699
Score:  0.489
Data Source:  STRINGDB
TMEM14B
Tbio
Novelty:  0.98487964
Score:  0.455
Data Source:  STRINGDB
SRP14
Tbio
Novelty:  0.03745351
Score:  0.45
Data Source:  STRINGDB
LRRC57
Tdark
Novelty:  5.85929893
Score:  0.44
Data Source:  STRINGDB
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
3
2
3
95.2
sex hormone-binding globulin measurement
6
1
6
87.8
platelet crit
1
1
1
85.9
platelet count
1
1
1
85.4
mean corpuscular hemoglobin concentration
1
1
1
77.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
3
95.2
sex hormone-binding globulin measurement
6
87.8
platelet crit
1
85.9
platelet count
1
85.4
mean corpuscular hemoglobin concentration
1
77.7
Find similar targets by:
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
small EDRK-rich factor 2
VGNC:13421
100615333
Mouse
MGI:1337041
378702
Rat
RGD:1588368
502663
Dog
small EDRK-rich factor 2
VGNC:49647
478280
Species
Name
OMA
EggNOG
Inparanoid
Chimp
small EDRK-rich factor 2
Mouse
Rat
Dog
small EDRK-rich factor 2
Publication Statistics
PubMed Score 4.52
PubMed score by year
PubTator Score 1.05
PubTator score by year