You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
RPL24
60S ribosomal protein L24

Protein Summary
Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from S. cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000394077
  • ENSP00000377640
  • ENSG00000114391

Symbol
  • L24
  • HEL-S-310
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
interacting protein
1
small molecule perturbation
1
phenotype
0.87
transcription factor binding site profile
0.84


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.19   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.19   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
1
1
34.8
body height
1
1
1
6.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
34.8
body height
1
6.3
Orthologs (17)
1 – 5 of 17
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein L24
740475
Macaque
ribosomal protein L24
702381
Mouse
MGI:1915443
68193
Rat
RGD:621191
64307
Dog
ribosomal protein L24
VGNC:53086
478547
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein L24
Macaque
ribosomal protein L24
Mouse
Rat
Dog
ribosomal protein L24
Protein Structure (7 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P83731-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 5 of 7
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (38)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Gene Ontology Terms (23)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
BHF-UCL
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (445)
1 – 10 of 445
NAP1L1
Tbio
Novelty:  0.03895314
p_int:  0.997958651
p_ni:  0.002041349
Score:  0.521
Data Source:  BioPlex,STRINGDB
DEFA5
Tbio
Novelty:  0.00863727
p_int:  0.953813824
p_ni:  0.046186176
Score:  0.163
Data Source:  BioPlex,STRINGDB
KCTD12
Tchem
Novelty:  0.0386637
p_int:  0.774332833
p_ni:  0.225667167
Data Source:  BioPlex
RPL39
Tbio
Novelty:  0.0307397
Score:  0.999
Data Source:  STRINGDB
RPL35
Tbio
Novelty:  0.03722634
Score:  0.999
Data Source:  STRINGDB
FAU
Tbio
Novelty:  0.01170009
Score:  0.999
Data Source:  STRINGDB
RPL18
Tbio
Novelty:  0.01765545
Score:  0.999
Data Source:  STRINGDB
RPL10
Tbio
Novelty:  0.01299391
Score:  0.999
Data Source:  STRINGDB
RPL36
Tbio
Novelty:  0.02259932
Score:  0.999
Data Source:  STRINGDB
RPL6
Tbio
Novelty:  0.01742007
Score:  0.999
Data Source:  STRINGDB
Publication Statistics
PubMed Score  41.19

PubMed score by year
PubTator Score  7.26

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: