Tbio RBP5 Retinol-binding protein 5

Protein Summary

Description

Intracellular transport of retinol. The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016]

Uniprot Accession IDs

• P82980
• Q53FB1

Gene Name

• RBP5

Ensembl ID

• ENST00000266560
• ENSP00000266560
• ENSG00000139194

Symbol

• CRBP3
• CRBPIII
• HRBPiso
• CRBP-III

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	1
pathway	0.88
cell line	0.6
transcription factor	0.6
protein domain	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.85   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 180   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.85   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 180   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0