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Tdark
MRPS9
28S ribosomal protein S9, mitochondrial

Protein Summary
Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258455
  • ENSP00000258455
  • ENSG00000135972

Symbol
  • RPMS9
  • S9mt
  • RPMS9
  • MRP-S9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.98
virus perturbation
0.97
histone modification site profile
0.89
kinase perturbation
0.81
cellular component
0.71


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
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These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.89   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 169   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.89   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
mitochondrial ribosomal protein S9
VGNC:308
459466
Macaque
mitochondrial ribosomal protein S9
712968
Mouse
MGI:1916777
69527
Rat
RGD:1306558
301371
Dog
mitochondrial ribosomal protein S9
VGNC:43427
474545
Species
Name
OMA
EggNOG
Inparanoid
Chimp
mitochondrial ribosomal protein S9
Macaque
mitochondrial ribosomal protein S9
Mouse
Rat
Dog
mitochondrial ribosomal protein S9
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P82933-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (7)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Mitochondrial translation
Reactome
Mitochondrial translation elongation
Reactome
Mitochondrial translation initiation
Reactome
Mitochondrial translation termination
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Mitochondrial translation
Mitochondrial translation elongation
Mitochondrial translation initiation
Mitochondrial translation termination
Gene Ontology Terms (10)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (301)
1 – 10 of 301
MRPS34
Tbio
Novelty:  0.29355603
p_int:  0.999615869
p_ni:  0.000384131
Score:  0.976
Data Source:  BioPlex,STRINGDB
MRPS18C
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Novelty:  0.42868428
p_int:  0.999576534
p_ni:  0.000423466
Score:  0.996
Data Source:  BioPlex,STRINGDB
MRPS27
Tbio
Novelty:  0.22058227
p_int:  0.999452564
p_ni:  0.000547436
Score:  0.986
Data Source:  BioPlex,STRINGDB
MRPS15
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Novelty:  0.37070563
p_int:  0.998719477
p_ni:  0.001280523
Score:  0.999
Data Source:  BioPlex,STRINGDB
MRPS17
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Novelty:  0.46103276
p_int:  0.997877267
p_ni:  0.002122733
Score:  0.953
Data Source:  BioPlex,STRINGDB
MRPS11
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Novelty:  0.29449255
p_int:  0.997834276
p_ni:  0.002165724
Score:  0.999
Data Source:  BioPlex,STRINGDB
MRPS31
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Novelty:  0.28807342
p_int:  0.997731753
p_ni:  0.002268247
Score:  0.998
Data Source:  BioPlex,STRINGDB
MRPS25
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Novelty:  0.59354314
p_int:  0.995579521
p_ni:  0.004420479
Score:  0.996
Data Source:  BioPlex,STRINGDB
TRMT10B
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Family:  Enzyme
Novelty:  0.61950381
p_int:  0.988406127
p_ni:  0.011593873
Score:  0.595
Data Source:  BioPlex,STRINGDB
ZNF707
Tdark
Family:  TF
Novelty:  1.42194815
p_int:  0.987650057
p_ni:  0.012349943
Score:  0.328
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  3.89

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer