Tbio PRLH Prolactin-releasing peptide

Protein Summary

Description

Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.

Uniprot Accession IDs

• P81277
• PrRP

Gene Name

• PRLH

Ensembl ID

• ENST00000165524
• ENSP00000165524
• ENSG00000071677

Symbol

• PRH
• PRH
• PRRP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease	0.67
cell line	0.49
biological process	0.46
phenotype	0.45
tissue	0.44

Protein Classes

DTO Classes

Prolactin-releasing Peptide Receptor

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 200.89   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 49   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 200.89   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 49   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0