SIM1
Single-minded homolog 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.85 | ||
gene perturbation | 0.8 | ||
PubMedID | 0.6 | ||
phenotype | 0.56 | ||
disease | 0.54 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hemoglobin measurement | 1 | 1 | 1 | 58.4 | |||||
balding measurement | 1 | 2 | 2 | 56.8 | |||||
hematocrit | 1 | 1 | 1 | 56.2 | |||||
neuroticism measurement | 3 | 3 | 1 | 5.6 | 53.7 | ||||
glomerular filtration rate | 2 | 2 | 2 | 47.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hemoglobin measurement | 1 | 58.4 | |||||
balding measurement | 2 | 56.8 | |||||
hematocrit | 1 | 56.2 | |||||
neuroticism measurement | 1 | 5.6 | 53.7 | ||||
glomerular filtration rate | 2 | 47.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | SIM bHLH transcription factor 1 | VGNC:7909 | 472084 | |||||
Macaque | single-minded family bHLH transcription factor 1 | 695324 | ||||||
Mouse | MGI:98306 | 20464 | ||||||
Rat | RGD:1309949 | 309888 | ||||||
Dog | SIM bHLH transcription factor 1 | VGNC:46174 | 481937 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | SIM bHLH transcription factor 1 | |||||
Macaque | single-minded family bHLH transcription factor 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | SIM bHLH transcription factor 1 | |||||
PMID | Year | Title |
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