ABAT
4-aminobutyrate aminotransferase, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.99 | ||
transcription factor perturbation | 0.96 | ||
kinase perturbation | 0.81 | ||
molecular function | 0.81 | ||
cellular component | 0.77 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Degradation of GABA | ||||
Reactome | GABA synthesis, release, reuptake and degradation | ||||
Reactome | Neuronal System | ||||
Reactome | Neurotransmitter release cycle | ||||
Reactome | Transmission across Chemical Synapses | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Degradation of GABA | ||||
GABA synthesis, release, reuptake and degradation | ||||
Neuronal System | ||||
Neurotransmitter release cycle | ||||
Transmission across Chemical Synapses | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
response to opioid | 1 | 1 | 1 | 21.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
response to opioid | 1 | 21.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | 4-aminobutyrate aminotransferase | VGNC:13649 | 453903 | |||||
Mouse | MGI:2443582 | 268860 | ||||||
Rat | RGD:620948 | 81632 | ||||||
Dog | 4-aminobutyrate aminotransferase | VGNC:37421 | 479856 | |||||
Horse | 4-aminobutyrate aminotransferase | VGNC:14897 | 100051470 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | 4-aminobutyrate aminotransferase | |||||
Mouse | ||||||
Rat | ||||||
Dog | 4-aminobutyrate aminotransferase | |||||
Horse | 4-aminobutyrate aminotransferase | |||||
PMID | Year | Title |
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