You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
SLC35B1
Solute carrier family 35 member B1

Protein Summary
Description
Probable sugar transporter. This gene encodes a nucleotide sugar transporter which is a member of solute carrier family 35. The transporters in this family are highly conserved hydrophobic proteins with multiple transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000240333
  • ENSP00000240333
  • ENSG00000121073
  • ENST00000649906
  • ENSP00000497423

Symbol
  • UGTREL1
  • UGTREL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
kinase perturbation
0.95
virus perturbation
0.94
transcription factor binding site profile
0.9
histone modification site profile
0.83


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.31   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 62   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.31   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (61)
1 – 10 of 61
SLC35D1
Tbio
Family:  Transporter
Novelty:  0.08762897
Score:  0.912
Data Source:  STRINGDB
DNAJB11
Tbio
Novelty:  0.02588745
Score:  0.873
Data Source:  STRINGDB
MANF
Tbio
Novelty:  0.00586461
Score:  0.823
Data Source:  STRINGDB
SLC35C1
Tbio
Family:  Transporter
Novelty:  0.05958023
Score:  0.793
Data Source:  STRINGDB
SLC35A2
Tbio
Family:  Transporter
Novelty:  0.00072521
Score:  0.744
Data Source:  STRINGDB
ERG28
Tbio
Novelty:  0.04267481
Score:  0.714
Data Source:  STRINGDB
YIPF6
Tdark
Novelty:  0.04316252
Score:  0.712
Data Source:  STRINGDB
TM9SF4
Tbio
Novelty:  0.10441964
Score:  0.705
Data Source:  STRINGDB
MTCH2
Tbio
Novelty:  0.01794294
Score:  0.696
Data Source:  STRINGDB
SLC35A5
Tdark
Family:  Transporter
Novelty:  0.89836104
Score:  0.68
Data Source:  STRINGDB
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
4
4
97.8
mean corpuscular volume
3
3
4
96.9
mosaic loss of chromosome Y measurement
3
2
3
86.9
mean corpuscular hemoglobin concentration
1
1
1
85.6
red blood cell distribution width
2
2
3
63.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
4
97.8
mean corpuscular volume
4
96.9
mosaic loss of chromosome Y measurement
3
86.9
mean corpuscular hemoglobin concentration
1
85.6
red blood cell distribution width
3
63.6
Find similar targets by:
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
solute carrier family 35 member B1
699953
Anole lizard
solute carrier family 35 member B1
100553382
S.cerevisiae
S000006165
855832
Species
Name
OMA
EggNOG
Inparanoid
Macaque
solute carrier family 35 member B1
Anole lizard
solute carrier family 35 member B1
S.cerevisiae
Publication Statistics
PubMed Score 4.31
PubMed score by year
PubTator Score 1.74
PubTator score by year