Tbio CTAG1A Cancer/testis antigen 1

Protein Summary

Description

The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]

Uniprot Accession IDs

• P78358
• A1L417
• B7WNL9
• Q7LBY4
• Q9NY13

Gene Name

• CTAG1A

Ensembl ID

• ENST00000328435
• ENSP00000332602
• ENSG00000184033
• ENST00000359887
• ENSP00000352953
• ENST00000599837
• ENSP00000469441
• ENSG00000268651

Symbol

• CTAG
• CTAG1
• ESO1
• LAGE2
• LAGE2A
• CTAG
• ESO1
• CT6.1
• CTAG1
• LAGE-2
• LAGE2B
• NY-ESO-1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease	0.38
gene perturbation	0.36
biological term	0.33
interacting protein	0.31
small molecule perturbation	0.24

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 777.83   (req: < 5)

Gene RIFs: 97   (req: <= 3)

Antibodies: 681   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 777.83   (req: >= 5)

Gene RIFs: 97   (req: > 3)

Antibodies: 681   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0