You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TMSB10
Thymosin beta-10

Protein Summary
Description
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000233143
  • ENSP00000233143
  • ENSG00000034510

Symbol
  • PTMB10
  • THYB10
  • TB10
  • MIG12
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
1
transcription factor perturbation
0.97
disease perturbation
0.87
PubMedID
0.84
transcription factor binding site profile
0.78


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 129.32   (req: < 5)
Gene RIFs: 21   (req: <= 3)
Antibodies: 97   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 129.32   (req: >= 5)
Gene RIFs: 21   (req: > 3)
Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (15)
1 – 10 of 15
GPNMB
Tbio
Novelty: 0.00618732
Score: 0.845
Data Source: STRINGDB
S100A6
Tbio
Novelty: 0.00176164
Score: 0.78
Data Source: STRINGDB
BAMBI
Tbio
Novelty: 0.00736806
Score: 0.75
Data Source: STRINGDB
PMEL
Tbio
Novelty: 0.00116525
Score: 0.715
Data Source: STRINGDB
TBRG1
Tbio
Novelty: 0.02003439
Score: 0.59
Data Source: STRINGDB
PFN1
Tbio
Novelty: 0.0048861
Score: 0.587
Data Source: STRINGDB
ACTB
Tbio
Novelty: 0.00006048
Score: 0.509
Data Source: STRINGDB
VEGFA
Tclin
Novelty: 0.0000378
Score: 0.499
Data Source: STRINGDB
APOL2
Tbio
Novelty: 0.06076255
Score: 0.45
Data Source: STRINGDB
REEP5
Tbio
Novelty: 0.00160455
Score: 0.429
Data Source: STRINGDB
Publication Statistics
PubMed Score  129.32

PubMed score by year
PubTator Score  57.27

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer