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Tbio
RPL38
60S ribosomal protein L38

Protein Summary
Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome, including one located in the promoter region of the type 1 angiotensin II receptor gene. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000311111
  • ENSP00000309830
  • ENSG00000172809
  • ENST00000439590
  • ENSP00000390279
  • ENST00000533498
  • ENSP00000434243

Symbol
  • L38
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
1
kinase perturbation
1
phenotype
1
transcription factor binding site profile
0.97
disease perturbation
0.95


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.48   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.48   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (6)
1 – 5 of 6
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (35)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Gene Ontology Terms (20)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (413)
1 – 10 of 413
MRPL34
Tdark
Novelty: 1.17388411
p_int: 0.985284403
p_ni: 0.014715597
Score: 0.33
Data Source: BioPlex,STRINGDB
RPS6
Tbio
Novelty: 0.00122241
Score: 0.999
Data Source: STRINGDB
RPL13A
Tbio
Novelty: 0.00503698
Score: 0.999
Data Source: STRINGDB
RPL7
Tbio
Novelty: 0.00552644
Score: 0.999
Data Source: STRINGDB
RPS15
Tbio
Novelty: 0.00635155
Score: 0.999
Data Source: STRINGDB
RPL23A
Tbio
Novelty: 0.02951947
Score: 0.999
Data Source: STRINGDB
RPL10A
Tbio
Novelty: 0.01747453
Score: 0.999
Data Source: STRINGDB
RPL3
Tbio
Novelty: 0.00566964
Score: 0.999
Data Source: STRINGDB
RPL31
Tbio
Novelty: 0.03427872
Score: 0.999
Data Source: STRINGDB
RPS2
Tbio
Novelty: 0.00412313
Score: 0.999
Data Source: STRINGDB
Publication Statistics
PubMed Score  31.48

PubMed score by year
PubTator Score  17.47

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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