FKBP1A
Peptidyl-prolyl cis-trans isomerase FKBP1A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
disease perturbation | 1 | ||
transcription factor perturbation | 1 | ||
kinase perturbation | 0.98 | ||
molecular function | 0.97 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Calcineurin activates NFAT | ||||
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Reactome | Downstream signaling events of B Cell Receptor (BCR) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Calcineurin activates NFAT | ||||
Disease | ||||
Diseases of signal transduction | ||||
Downstream signaling events of B Cell Receptor (BCR) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Non-traceable Author Statement (NAS) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 2 | 2 | 2 | 74.1 | |||||
myeloperoxidase measurement | 1 | 1 | 1 | 15.8 | |||||
body mass index | 2 | 1 | 2 | 6.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 2 | 74.1 | |||||
myeloperoxidase measurement | 1 | 15.8 | |||||
body mass index | 2 | 6.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | FK506 binding protein 1A | VGNC:14132 | 749347 | |||||
Mouse | MGI:95541 | 14225 | ||||||
Rat | RGD:2617 | 25639 | ||||||
Horse | FK506 binding protein 1A | 100629541 | ||||||
Cow | FK506 binding protein 1A | 614795 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | FK506 binding protein 1A | |||||
Mouse | ||||||
Rat | ||||||
Horse | FK506 binding protein 1A | |||||
Cow | FK506 binding protein 1A | |||||
PMID | Year | Title |
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