You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
RPL32
60S ribosomal protein L32

Protein Summary
Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000396953
  • ENSP00000380156
  • ENSG00000144713
  • ENST00000396957
  • ENSP00000380158
  • ENST00000429711
  • ENSP00000416429
  • ENST00000435983
  • ENSP00000388674

Symbol
  • L32
  • PP9932
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
1
interacting protein
0.99
transcription factor binding site profile
0.9
disease perturbation
0.87
biological process
0.71


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 334.53   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 334.53   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
0
1.1
88
waist-hip ratio
1
5
5
61.4
electrocardiography
1
1
14
59
BMI-adjusted waist-hip ratio
1
4
4
56.6
creatine kinase measurement
1
1
1
45.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
88
waist-hip ratio
5
61.4
electrocardiography
14
59
BMI-adjusted waist-hip ratio
4
56.6
creatine kinase measurement
1
45.7
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
60S ribosomal protein L32
450727
Macaque
ribosomal protein L32
694196
Mouse
MGI:98038
19951
Dog
ribosomal protein L32
607481
Horse
ribosomal protein L32
100056766
Species
Name
OMA
EggNOG
Inparanoid
Chimp
60S ribosomal protein L32
Macaque
ribosomal protein L32
Mouse
Dog
ribosomal protein L32
Horse
ribosomal protein L32
Protein Structure (6 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P62910-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 5 of 6
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (36)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Gene Ontology Terms (11)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Non-traceable Author Statement (NAS)
UniProtKB
Protein-Protein Interactions (439)
1 – 10 of 439
MAK16
Tdark
Novelty:  0.07717917
p_int:  0.970324158
p_ni:  0.029675842
Score:  0.885
Data Source:  BioPlex,STRINGDB
CNBP
Tbio
Novelty:  0.00404247
p_int:  0.95988206
p_ni:  0.04011794
Score:  0.494
Data Source:  BioPlex,STRINGDB
ZNF512
Tbio
Family:  TF
Novelty:  0.08783629
p_int:  0.939686294
p_ni:  0.060313706
Score:  0.49
Data Source:  BioPlex,STRINGDB
RPL30
Tbio
Novelty:  0.0134194
p_int:  0.929863296
p_ni:  0.070136704
Score:  0.999
Data Source:  BioPlex,STRINGDB
RPL18A
Tbio
Novelty:  0.04612948
p_int:  0.926944127
p_ni:  0.073055873
Score:  0.999
Data Source:  BioPlex,STRINGDB
RBM34
Tdark
Novelty:  0.58131282
p_int:  0.920575441
p_ni:  0.079424559
Score:  0.56
Data Source:  BioPlex,STRINGDB
PUM3
Tbio
Novelty:  0.02344206
p_int:  0.919830266
p_ni:  0.080169734
Score:  0.573
Data Source:  BioPlex,STRINGDB
MAGEB10
Tdark
Novelty:  2.96156972
p_int:  0.916446862
p_ni:  0.083553138
Data Source:  BioPlex
RRP8
Tbio
Family:  Enzyme
Novelty:  0.04922797
p_int:  0.911535142
p_ni:  0.088464858
Score:  0.567
Data Source:  BioPlex,STRINGDB
RPS14
Tbio
Novelty:  0.00576737
p_int:  0.885104457
p_ni:  0.114895543
Score:  0.999
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  334.53

PubMed score by year
PubTator Score  92.54

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: