You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
RPL30
60S ribosomal protein L30

Protein Summary
Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30E family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U72 small nucleolar RNA gene, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000287038
  • ENSP00000287038
  • ENSG00000156482
  • ENST00000521291
  • ENSP00000428085

Symbol
  • L30
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
hub protein
0.98
drug perturbation
0.96
histone modification site profile
0.82
biological process
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.45   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 245   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.45   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 245   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (7)
1 – 5 of 7
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (37)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Gene Ontology Terms (18)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (514)
1 – 10 of 514
HIST1H1C
Tbio
Novelty: 0.00937936
p_int: 0.999994974
p_ni: 0.000005026
Score: 0.16
Data Source: BioPlex,STRINGDB
HIST1H1T
Tdark
Novelty: 0.01211318
p_int: 0.999766816
p_ni: 0.000233184
Data Source: BioPlex
RPL26L1
Tdark
Novelty: 2
p_int: 0.996263711
p_ni: 0.003736289
Score: 0.999
Data Source: BioPlex,STRINGDB
RRP8
Tbio
Family: Enzyme
Novelty: 0.00456854
p_int: 0.995970109
p_ni: 0.004029891
Score: 0.323
Data Source: BioPlex,STRINGDB
PUM3
Tbio
Novelty: 0.01145585
p_int: 0.993226897
p_ni: 0.006773103
Score: 0.371
Data Source: BioPlex,STRINGDB
RBM34
Tdark
Novelty: 1.05263158
p_int: 0.992378604
p_ni: 0.007621396
Score: 0.532
Data Source: BioPlex,STRINGDB
RBM28
Tbio
Novelty: 0.01991731
p_int: 0.986442314
p_ni: 0.013557673
p_wrong: 1.3e-8
Score: 0.313
Data Source: BioPlex,STRINGDB
NSA2
Tbio
Novelty: 0.09659243
p_int: 0.981863818
p_ni: 0.018136182
Score: 0.931
Data Source: BioPlex,STRINGDB
REXO4
Tbio
Family: Enzyme
Novelty: 0.02462595
p_int: 0.980151462
p_ni: 0.019848538
Score: 0.269
Data Source: BioPlex,STRINGDB
ZC3HAV1
Tbio
Novelty: 0.01794897
p_int: 0.977306344
p_ni: 0.022693656
Score: 0.543
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  37.45

PubMed score by year
PubTator Score  32.19

PubTator score by year
Amino Acid Sequence
Residue Counts
Sequence
MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTG
1-70
VHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK
70-115
MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK