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Tbio
RPS26
40S ribosomal protein S26

Protein Summary
Description
This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. Mutations in this gene are found in Diamond-Blackfan anemia 10. There are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Aug 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356464
  • ENSP00000348849
  • ENSG00000197728
  • ENST00000552361
  • ENSP00000450339
  • ENST00000646449
  • ENSP00000496643

Symbol
  • S26
  • eS26
  • DBA10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
interacting protein
1
kinase perturbation
0.99
transcription factor binding site profile
0.97
gene perturbation
0.96


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.45   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.45   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (440)
RPL19
Tbio
Novelty:  0.00756385
Score:  0.999
Data Source:  STRINGDB
RPLP1
Tbio
Novelty:  0.01471148
Score:  0.999
Data Source:  STRINGDB
RPL10
Tbio
Novelty:  0.01299391
Score:  0.999
Data Source:  STRINGDB
RPS28
Tbio
Novelty:  0.03303065
Score:  0.999
Data Source:  STRINGDB
RPS13
Tbio
Novelty:  0.0019983
Score:  0.999
Data Source:  STRINGDB
RPS24
Tbio
Novelty:  0.01928704
Score:  0.999
Data Source:  STRINGDB
RPS7
Tbio
Novelty:  0.00745987
Score:  0.999
Data Source:  STRINGDB
RPL27
Tbio
Novelty:  0.0157566
Score:  0.999
Data Source:  STRINGDB
RPS17
Tbio
Novelty:  0.00942675
Score:  0.999
Data Source:  STRINGDB
RPL23
Tbio
Novelty:  0.02741113
Score:  0.999
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (64)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (R-HSA-72662)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 36
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Name
Explore in Pharos
Explore in Source
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (50)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
7
6
6
3.4
97.2
6
5
0
1.3
95.2
mathematical ability
4
4
4
94.3
8
8
0
1.1
93.5
3
3
0
1.3
91.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
6
3.4
97.2
0
1.3
95.2
mathematical ability
4
94.3
0
1.1
93.5
0
1.3
91.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein S26
VGNC:13438
747446
Mouse
MGI:1351628
27370
Horse
ribosomal protein S26
100034009
Cow
ribosomal protein S26
509426
Pig
ribosomal protein S26
100037997
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein S26
Mouse
Horse
ribosomal protein S26
Cow
ribosomal protein S26
Pig
ribosomal protein S26
Publication Statistics
PubMed Score 53.45
PubMed score by year
PubTator Score 27.63
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title