Tbio RPS26 40S ribosomal protein S26

Protein Summary

Description

This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. Mutations in this gene are found in Diamond-Blackfan anemia 10. There are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Aug 2017]

Uniprot Accession IDs

• P62854
• P02383
• P70394
• Q06722
• Q3MHD8
• Q6IRY4

Gene Name

• RPS26

Ensembl ID

• ENST00000356464
• ENSP00000348849
• ENSG00000197728
• ENST00000552361
• ENSP00000450339
• ENST00000646449
• ENSP00000496643

Symbol

• S26
• eS26
• DBA10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	1
interacting protein	1
kinase perturbation	0.99
transcription factor binding site profile	0.97
gene perturbation	0.96

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / 40s Ribosomal Protein S26

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / 40s Ribosomal Protein S26

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.36   (req: < 5)

Gene RIFs: 15   (req: <= 3)

Antibodies: 93   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.36   (req: >= 5)

Gene RIFs: 15   (req: > 3)

Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0