ESRRG
Estrogen-related receptor gamma
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
trait | 0.99 | ||
molecular function | 0.97 | ||
protein domain | 0.97 | ||
microRNA | 0.78 | ||
phenotype | 0.75 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Nuclear Receptor transcription pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Nuclear Receptor transcription pathway | ||||
RNA Polymerase II Transcription | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
autosomal dominant compelling helio-ophthalmic outburst syndrome | 1 | 1 | 0 | 1.3 | 86.4 | ||||
intraocular pressure measurement | 3 | 1 | 3 | 78.3 | |||||
mathematical ability | 3 | 4 | 5 | 73.7 | |||||
self reported educational attainment | 2 | 2 | 2 | 68.4 | |||||
testosterone measurement | 2 | 2 | 2 | 65.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
autosomal dominant compelling helio-ophthalmic outburst syndrome | 0 | 1.3 | 86.4 | ||||
intraocular pressure measurement | 3 | 78.3 | |||||
mathematical ability | 5 | 73.7 | |||||
self reported educational attainment | 2 | 68.4 | |||||
testosterone measurement | 2 | 65.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | estrogen related receptor gamma | VGNC:6793 | 457738 | |||||
Macaque | estrogen-related receptor gamma-like | 106992350 | ||||||
Mouse | MGI:1347056 | 26381 | ||||||
Rat | RGD:1303236 | 360896 | ||||||
Dog | estrogen related receptor gamma | VGNC:40481 | 478961 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | estrogen related receptor gamma | |||||
Macaque | estrogen-related receptor gamma-like | |||||
Mouse | ||||||
Rat | ||||||
Dog | estrogen related receptor gamma | |||||
PMID | Year | Title |
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