UBE2N
Ubiquitin-conjugating enzyme E2 N
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.99 | ||
interacting protein | 0.99 | ||
biological process | 0.98 | ||
molecular function | 0.98 | ||
kinase perturbation | 0.97 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | Antiviral mechanism by IFN-stimulated genes | ||||
Reactome | C-type lectin receptors (CLRs) | ||||
Reactome | CLEC7A (Dectin-1) signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
Antiviral mechanism by IFN-stimulated genes | ||||
C-type lectin receptors (CLRs) | ||||
CLEC7A (Dectin-1) signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 2 | 2 | 2 | 82 | |||||
red blood cell distribution width | 2 | 2 | 2 | 76.7 | |||||
reticulocyte measurement | 3 | 2 | 3 | 66.6 | |||||
reticulocyte count | 3 | 2 | 3 | 58.9 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 54.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 2 | 82 | |||||
red blood cell distribution width | 2 | 76.7 | |||||
reticulocyte measurement | 3 | 66.6 | |||||
reticulocyte count | 3 | 58.9 | |||||
mean reticulocyte volume | 1 | 54.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ubiquitin conjugating enzyme E2 N | VGNC:5641 | 452125 | |||||
Macaque | ubiquitin conjugating enzyme E2 N | 715437 | ||||||
Mouse | MGI:1934835 | 93765 | ||||||
Rat | RGD:621096 | 116725 | ||||||
Horse | ubiquitin-conjugating enzyme E2 N | 102150222 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ubiquitin conjugating enzyme E2 N | |||||
Macaque | ubiquitin conjugating enzyme E2 N | |||||
Mouse | ||||||
Rat | ||||||
Horse | ubiquitin-conjugating enzyme E2 N | |||||
PMID | Year | Title |
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