UBE2M
NEDD8-conjugating enzyme Ubc12
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.99 | ||
molecular function | 0.98 | ||
disease perturbation | 0.79 | ||
hub protein | 0.75 | ||
transcription factor binding site profile | 0.7 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | C-type lectin receptors (CLRs) | ||||
Reactome | CLEC7A (Dectin-1) signaling | ||||
Reactome | Class I MHC mediated antigen processing & presentation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
C-type lectin receptors (CLRs) | ||||
CLEC7A (Dectin-1) signaling | ||||
Class I MHC mediated antigen processing & presentation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 2 | 3 | 78.7 | |||||
mathematical ability | 3 | 2 | 3 | 64 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 49.5 | |||||
red blood cell distribution width | 1 | 1 | 1 | 49.5 | |||||
intelligence | 1 | 1 | 0 | 6.2 | 38.2 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 3 | 78.7 | |||||
mathematical ability | 3 | 64 | |||||
mean reticulocyte volume | 1 | 49.5 | |||||
red blood cell distribution width | 1 | 49.5 | |||||
intelligence | 0 | 6.2 | 38.2 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:108278 | 22192 | ||||||
Rat | RGD:1307614 | 361509 | ||||||
Dog | ubiquitin conjugating enzyme E2 M | VGNC:48059 | 484221 | |||||
Horse | ubiquitin conjugating enzyme E2 M | VGNC:24724 | 100064883 | |||||
Cow | ubiquitin conjugating enzyme E2 M | VGNC:36589 | 613343 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | ubiquitin conjugating enzyme E2 M | |||||
Horse | ubiquitin conjugating enzyme E2 M | |||||
Cow | ubiquitin conjugating enzyme E2 M | |||||
PMID | Year | Title |
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