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Tbio
SRP54
Signal recognition particle 54 kDa protein

Protein Summary
Description
Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216774
  • ENSP00000216774
  • ENSG00000100883
  • ENST00000546080
  • ENSP00000440629
  • ENST00000556994
  • ENSP00000451818
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.99
interacting protein
0.94
protein domain
0.92
disease perturbation
0.9
cellular component
0.82


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 205.47   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 187   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 205.47   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 187   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0