RAB8A
Ras-related protein Rab-8A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 1 | ||
molecular function | 0.99 | ||
virus perturbation | 0.99 | ||
disease perturbation | 0.97 | ||
interacting protein | 0.96 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Anchoring of the basal body to the plasma membrane | ||||
Reactome | Cargo trafficking to the periciliary membrane | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | Cilium Assembly | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Anchoring of the basal body to the plasma membrane | ||||
Cargo trafficking to the periciliary membrane | ||||
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
Cilium Assembly | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 7 | 8 | 11 | 99.6 | |||||
platelet count | 6 | 5 | 6 | 11.4 | 98.7 | ||||
platelet crit | 2 | 2 | 2 | 92.6 | |||||
mean corpuscular hemoglobin concentration | 2 | 2 | 2 | 91 | |||||
red blood cell distribution width | 2 | 2 | 2 | 78.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 11 | 99.6 | |||||
platelet count | 6 | 11.4 | 98.7 | ||||
platelet crit | 2 | 92.6 | |||||
mean corpuscular hemoglobin concentration | 2 | 91 | |||||
red blood cell distribution width | 2 | 78.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | RAB8A, member RAS oncogene family | VGNC:7571 | 468760 | |||||
Macaque | RAB8A, member RAS oncogene family | 100423251 | ||||||
Mouse | MGI:96960 | 17274 | ||||||
Rat | RGD:621144 | 117103 | ||||||
Dog | RAB8A, member RAS oncogene family | VGNC:45295 | 403773 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | RAB8A, member RAS oncogene family | |||||
Macaque | RAB8A, member RAS oncogene family | |||||
Mouse | ||||||
Rat | ||||||
Dog | RAB8A, member RAS oncogene family | |||||
PMID | Year | Title |
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