Tbio ELOF1 Transcription elongation factor 1 homolog

Protein Summary

Description

Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

Uniprot Accession IDs

• P60002
• Q8R1J7
• Q96II4

Gene Name

• ELOF1

Ensembl ID

• ENST00000252445
• ENSP00000252445
• ENSG00000130165
• ENST00000586120
• ENSP00000467914
• ENST00000590700
• ENSP00000467264

Symbol

• ELF1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.95
histone modification site profile	0.79
kinase perturbation	0.6
transcription factor binding site profile	0.59
tissue	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.72   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 77   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.72   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0