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Tdark
ZNF445
Zinc finger protein 445

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000396077
  • ENSP00000379387
  • ENSG00000185219
  • ENST00000425708
  • ENSP00000413073
  • ENST00000634579
  • ENSP00000489139
  • ENSG00000283034
  • ENST00000635479
  • ENSP00000489368

Symbol
  • ZKSCAN15
  • ZNF168
  • ZNF168
  • ZSCAN47
  • ZKSCAN15
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
histone modification site profile
0.83
transcription factor perturbation
0.74
transcription factor binding site profile
0.58
cell line
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.38   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.38   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
SETDB2
Tbio
Family:  TF; Epigenetic
Novelty:  0.05560622
p_int:  0.999993696
p_ni:  0.000006304
Score:  0.275
Data Source:  BioPlex,STRINGDB
NDEL1
Tbio
Novelty:  0.01241819
p_int:  0.999733556
p_ni:  0.000266444
Data Source:  BioPlex
ZNF263
Tbio
Family:  TF
Novelty:  0.098799
p_int:  0.996839535
p_ni:  0.003160291
p_wrong:  1.74e-7
Data Source:  BioPlex
ZNF287
Tdark
Family:  TF
Novelty:  1.01445884
p_int:  0.996586716
p_ni:  0.003412272
p_wrong:  0.000001012
Data Source:  BioPlex
SYT12
Tbio
Novelty:  0.03410873
p_int:  0.993960195
p_ni:  0.006039805
Data Source:  BioPlex
ZNF169
Tdark
Family:  TF
Novelty:  1.09432767
p_int:  0.9924436
p_ni:  0.0075564
Data Source:  BioPlex
ZNF483
Tdark
Family:  TF
Novelty:  0.39891191
p_int:  0.989444206
p_ni:  0.010555792
p_wrong:  1e-9
Score:  0.163
Data Source:  BioPlex,STRINGDB
ZNF707
Tdark
Family:  TF
Novelty:  1.42194815
p_int:  0.985684263
p_ni:  0.014315737
Data Source:  BioPlex
CACNG5
Tdark
Family:  IC
Novelty:  0.52705448
p_int:  0.985284511
p_ni:  0.014715489
p_wrong:  1e-9
Data Source:  BioPlex
ZNF324B
Tdark
Family:  TF
Novelty:  1.89922228
p_int:  0.985278547
p_ni:  0.014721444
p_wrong:  9e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
daytime rest measurement
1
1
1
24.5
C-reactive protein measurement
1
1
1
14.2
macrophage inflammatory protein 1b measurement
1
1
1
7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
daytime rest measurement
1
24.5
C-reactive protein measurement
1
14.2
macrophage inflammatory protein 1b measurement
1
7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 445
715227
Mouse
MGI:2143340
235682
Rat
RGD:1559144
301076
Dog
zinc finger protein 445
VGNC:48730
477008
Cow
zinc finger protein 445
VGNC:37277
540408
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 445
Mouse
Rat
Dog
zinc finger protein 445
Cow
zinc finger protein 445
Publication Statistics
PubMed Score 2.38
PubMed score by year
PubTator Score 0.70
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title