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Tbio
RAB15
Ras-related protein Rab-15

Protein Summary
Description
May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000267512
  • ENSP00000267512
  • ENSG00000139998
  • ENST00000533601
  • ENSP00000434103
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.91
transcription factor perturbation
0.88
interacting protein
0.82
histone modification site profile
0.79
cellular component
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.47   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.47   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
1
1
59.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
59.4
Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
RAB geranylgeranylation
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational protein modification
RAB geranylgeranylation
Gene Ontology Terms (17)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (86)
1 – 10 of 86
H2AFB1
Tbio
Novelty: 0.08770329
p_int: 0.999102332
p_ni: 8.39e-7
p_wrong: 0.000896829
Data Source: BioPlex
RAP1GDS1
Tbio
Family: Enzyme
Novelty: 0.06140479
p_int: 0.962678244
p_ni: 0.037321756
Score: 0.187
Data Source: BioPlex,STRINGDB
TOR1AIP2
Tbio
Novelty: 0.08912351
p_int: 0.874362487
p_ni: 0.125637513
Score: 0.189
Data Source: BioPlex,STRINGDB
RAB33B
Tbio
Family: Enzyme
Novelty: 0.06381712
Score: 0.933
Data Source: STRINGDB
CHM
Tbio
Family: Enzyme
Novelty: 0.00226278
Score: 0.932
Data Source: STRINGDB
RAB33A
Tbio
Family: Enzyme
Novelty: 0.11617001
Score: 0.931
Data Source: STRINGDB
CHML
Tbio
Family: Enzyme
Novelty: 0.00509709
Score: 0.93
Data Source: STRINGDB
RAB19
Tbio
Family: Enzyme
Novelty: 0.15847208
Score: 0.93
Data Source: STRINGDB
RAB1B
Tbio
Family: Enzyme
Novelty: 0.02156819
Score: 0.929
Data Source: STRINGDB
RAB43
Tbio
Family: Enzyme
Novelty: 0.07527576
Score: 0.928
Data Source: STRINGDB
Publication Statistics
PubMed Score  10.47

PubMed score by year
PubTator Score  7.43

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer