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Tbio
EVA1C
Protein eva-1 homolog C

Protein Summary
Description
Binds heparin.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300255
  • ENSP00000300255
  • ENSG00000166979
  • ENST00000382699
  • ENSP00000372146

Symbol
  • C21orf63
  • C21orf64
  • FAM176C
  • B18
  • B19
  • SUE21
  • PRED34
  • FAM176C
  • C21orf63
  • C21orf64
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.77
transcription factor
0.66
PubMedID
0.64
transcription factor binding site profile
0.57
gene perturbation
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.02   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 49   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.02   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 49   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (68)
1 – 10 of 68
TSPAN6
Tbio
Novelty:  0.11515803
p_int:  0.996497676
p_ni:  0.001306142
p_wrong:  0.002196181
Score:  0.158
Data Source:  BioPlex,STRINGDB
TYW1
Tbio
Family:  Enzyme
Novelty:  0.05117274
p_int:  0.995496839
p_ni:  0.004503161
Data Source:  BioPlex
PIGA
Tbio
Family:  Enzyme
Novelty:  0.00172769
p_int:  0.994147664
p_ni:  0.005852332
p_wrong:  4e-9
Score:  0.158
Data Source:  BioPlex,STRINGDB
BMPR1B
Tchem
Family:  Kinase
Novelty:  0.00698763
p_int:  0.994086216
p_ni:  0.000204657
p_wrong:  0.005709127
Score:  0.255
Data Source:  BioPlex,STRINGDB
PDZD8
Tbio
Novelty:  0.09015543
p_int:  0.992047685
p_ni:  0.007952315
Score:  0.221
Data Source:  BioPlex,STRINGDB
ATP2A3
Tchem
Family:  Transporter
Novelty:  0.0090982
p_int:  0.991733409
p_ni:  0.008266591
Data Source:  BioPlex
PNMA2
Tbio
Novelty:  0.00162709
p_int:  0.989640623
p_ni:  0.010359377
Data Source:  BioPlex
NRP1
Tchem
Novelty:  0.00153628
p_int:  0.987685698
p_ni:  0.012314302
Data Source:  BioPlex
SACM1L
Tbio
Family:  Enzyme
Novelty:  0.00499867
p_int:  0.982257178
p_ni:  0.017742822
Data Source:  BioPlex
EDA
Tbio
Novelty:  0.00352464
p_int:  0.980452843
p_ni:  0.004882969
p_wrong:  0.014664189
Data Source:  BioPlex
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Mutant Phenotype (IMP)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
1
3
80.2
serum gamma-glutamyl transferase measurement
1
1
1
35
intraocular pressure measurement
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
80.2
serum gamma-glutamyl transferase measurement
1
35
intraocular pressure measurement
1
17.8
Find similar targets by:
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
eva-1 homolog C
473956
Mouse
MGI:1918217
70967
Rat
RGD:1307569
360695
Dog
eva-1 homolog C
VGNC:40502
478402
Horse
eva-1 homolog C
VGNC:17708
100063805
Species
Name
OMA
EggNOG
Inparanoid
Chimp
eva-1 homolog C
Mouse
Rat
Dog
eva-1 homolog C
Horse
eva-1 homolog C
Publication Statistics
PubMed Score 4.02
PubMed score by year
PubTator Score 279.59
PubTator score by year