EEFSEC
Selenocysteine-specific elongation factor
Protein Summary
Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
- ENST00000254730
- ENSP00000254730
- ENSG00000132394
- ENST00000644579
- ENSP00000494933
- ENSG00000284869
- SELB
- SELB
- EFSEC
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.99 | ||
histone modification site profile | 0.86 | ||
transcription factor binding site profile | 0.82 | ||
interacting protein | 0.75 | ||
gene perturbation | 0.65 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 137.29 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 99 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 137.29 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 99 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0