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Tbio
NUP107
Nuclear pore complex protein Nup107

Protein Classes
Protein Summary
Description
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:12552102, PubMed:15229283). Required for the assembly of peripheral proteins into the NPC (PubMed:15229283, PubMed:12552102). May anchor NUP62 to the NPC (PubMed:15229283). This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000229179
  • ENSP00000229179
  • ENSG00000111581
  • ENST00000378905
  • ENSP00000368185
  • ENST00000539906
  • ENSP00000441448

Symbol
  • ODG6
  • NUP84
  • NPHS11
  • ODG6; GAMOS7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
histone modification site profile
0.92
interacting protein
0.86
transcription factor binding site profile
0.85
virus perturbation
0.79


Related Tools
GENEVA
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.15   (req: < 5)
Gene RIFs: 23   (req: <= 3)
Antibodies: 219   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.15   (req: >= 5)
Gene RIFs: 23   (req: > 3)
Antibodies: 219   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
nucleoporin 107
VGNC:5513
467062
Macaque
nucleoporin 107
718214
Mouse
MGI:2143854
103468
Rat
RGD:621160
116555
Dog
nucleoporin 107
VGNC:44044
474440
Species
Name
OMA
EggNOG
Inparanoid
Chimp
nucleoporin 107
Macaque
nucleoporin 107
Mouse
Rat
Dog
nucleoporin 107
Protein Data Bank (4)
1 – 4 of 4
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (83)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (R-HSA-141444)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 81
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Reactome
Amplification of signal from the kinetochores
Reactome
Antiviral mechanism by IFN-stimulated genes
Reactome
Cell Cycle
Reactome
Cell Cycle Checkpoints
Name
Explore in Pharos
Explore in Source
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Amplification of signal from the kinetochores
Antiviral mechanism by IFN-stimulated genes
Cell Cycle
Cell Cycle Checkpoints
Gene Ontology Terms (15)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (322)
1 – 10 of 322
NUP133
Tbio
Novelty: 0.02115225
p_int: 0.999915315
p_ni: 0.000084685
Score: 0.999
Data Source: BioPlex,STRINGDB
NUP43
Tbio
Novelty: 0.11571309
p_int: 0.999534073
p_ni: 0.000465927
Score: 0.999
Data Source: BioPlex,STRINGDB
SEC13
Tbio
Novelty: 0.00709413
p_int: 0.994727548
p_ni: 0.005272452
Score: 0.999
Data Source: BioPlex,STRINGDB
SPAST
Tbio
Novelty: 0.00303236
p_int: 0.986719872
p_ni: 0.013280128
Score: 0.705
Data Source: BioPlex,STRINGDB
UXS1
Tbio
Family: Enzyme
Novelty: 0.04671281
p_int: 0.835211247
p_ni: 0.164788753
Data Source: BioPlex
SIGLECL1
Tdark
p_int: 0.790388368
p_ni: 0.209611632
Data Source: BioPlex
CD70
Tbio
Novelty: 0.00420393
p_int: 0.75971839
p_ni: 0.24028161
Data Source: BioPlex
SEH1L
Tbio
Novelty: 0.03666501
Score: 0.999
Data Source: STRINGDB
NUP98
Tbio
Family: Enzyme
Novelty: 0.00401452
Score: 0.999
Data Source: STRINGDB
NUP160
Tbio
Novelty: 0.03667026
Score: 0.999
Data Source: STRINGDB
Publication Statistics
PubMed Score  52.15

PubMed score by year
PubTator Score  38.53

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer