NUP107
Nuclear pore complex protein Nup107
Protein Summary
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:12552102, PubMed:15229283). Required for the assembly of peripheral proteins into the NPC (PubMed:15229283, PubMed:12552102). May anchor NUP62 to the NPC (PubMed:15229283). This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- ENST00000229179
- ENSP00000229179
- ENSG00000111581
- ENST00000378905
- ENSP00000368185
- ENST00000539906
- ENSP00000441448
- ODG6
- NUP84
- NPHS11
- ODG6; GAMOS7
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.94 | ||
histone modification site profile | 0.92 | ||
interacting protein | 0.86 | ||
transcription factor binding site profile | 0.85 | ||
virus perturbation | 0.79 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 63.4 (req: < 5)
Gene RIFs: 23 (req: <= 3)
Antibodies: 219 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 63.4 (req: >= 5)
Gene RIFs: 23 (req: > 3)
Antibodies: 219 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0