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Tbio
SCAND1
SCAN domain-containing protein 1

Protein Summary
Description
May regulate transcriptional activity. This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305978
  • ENSP00000301995
  • ENSG00000171222
  • ENST00000373991
  • ENSP00000363103
  • ENST00000615116
  • ENSP00000481289

Symbol
  • SDP1
  • RAZ1
  • SDP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor binding site profile
0.83
cell type or tissue
0.74
transcription factor perturbation
0.68
transcription factor
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.54   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 200   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.54   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 200   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
ZSCAN32
Tdark
Family:  TF
Novelty:  3.83392226
p_int:  0.999994494
p_ni:  0.000005214
p_wrong:  2.92e-7
Score:  0.816
Data Source:  BioPlex,STRINGDB
ZSCAN20
Tdark
Family:  TF
Novelty:  0.37441538
p_int:  0.999978699
p_ni:  0.000021301
Score:  0.722
Data Source:  BioPlex,STRINGDB
ZNF24
Tbio
Family:  TF
Novelty:  0.02954446
p_int:  0.999974465
p_ni:  0.000024663
p_wrong:  8.72e-7
Score:  0.864
Data Source:  BioPlex,STRINGDB
ZKSCAN8
Tbio
Family:  TF
Novelty:  0.17881042
p_int:  0.999968556
p_ni:  0.000031378
p_wrong:  6.6e-8
Data Source:  BioPlex
ZNF232
Tdark
Family:  TF
Novelty:  0.68288358
p_int:  0.999966718
p_ni:  0.000022529
p_wrong:  0.000010753
Score:  0.747
Data Source:  BioPlex,STRINGDB
ZKSCAN4
Tbio
Family:  TF
Novelty:  0.33154485
p_int:  0.999910955
p_ni:  0.000089043
p_wrong:  2e-9
Score:  0.827
Data Source:  BioPlex,STRINGDB
ZNF397
Tbio
Family:  TF
Novelty:  0.60034816
p_int:  0.999896374
p_ni:  0.000031266
p_wrong:  0.000072361
Score:  0.816
Data Source:  BioPlex,STRINGDB
ZNF213
Tbio
Family:  TF
Novelty:  0.24190639
p_int:  0.999893245
p_ni:  0.000106746
p_wrong:  8e-9
Data Source:  BioPlex
ZNF444
Tdark
Family:  TF
Novelty:  0.21564163
p_int:  0.999874743
p_ni:  0.000125218
p_wrong:  3.9e-8
Score:  0.735
Data Source:  BioPlex,STRINGDB
ZNF263
Tbio
Family:  TF
Novelty:  0.098799
p_int:  0.999756749
p_ni:  0.000212256
p_wrong:  0.000030995
Score:  0.384
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
3
3
4
97.3
suntan
1
1
1
87.8
BMI-adjusted hip circumference
3
4
4
85
1
1
0
1.3
71.5
1
1
0
1.3
62.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
4
97.3
suntan
1
87.8
BMI-adjusted hip circumference
4
85
0
1.3
71.5
0
1.3
62.8
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SCAN domain containing 1
VGNC:14292
458213
Macaque
SCAN domain containing 1
711046
Mouse
MGI:1343132
19018
Rat
RGD:1308530
362252
Dog
SCAN domain containing 1
VGNC:54728
609014
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SCAN domain containing 1
Macaque
SCAN domain containing 1
Mouse
Rat
Dog
SCAN domain containing 1
Publication Statistics
PubMed Score 15.54
PubMed score by year
PubTator Score 11.91
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title