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Tchem
HUNK
Hormonally up-regulated neu tumor-associated kinase

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000270112
  • ENSP00000270112
  • ENSG00000142149

Symbol
  • MAKV
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
protein domain
0.73
gene perturbation
0.71
microRNA
0.7
PubMedID
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.23   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 329   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.23   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 329   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Active Ligands (1)
1 – 1 of 1
CHEMBL1721885
chemical structure image
Gene Ontology Terms (8)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (30)
1 – 10 of 30
PIP
Tbio
Novelty: 0.00208509
p_int: 0.999999953
p_ni: 4.6e-8
p_wrong: 1e-9
Data Source: BioPlex
RABEP1
Tbio
Family: Enzyme
Novelty: 0.02318446
Score: 0.697
Data Source: STRINGDB
ALX3
Tbio
Family: TF
Novelty: 0.02711914
Score: 0.516
Data Source: STRINGDB
DLEU7
Tdark
Novelty: 0.08581635
Score: 0.512
Data Source: STRINGDB
PIRT
Tdark
Novelty: 0.03227623
Score: 0.511
Data Source: STRINGDB
GABRB1
Tclin
Family: IC
Novelty: 0.02895574
Score: 0.511
Data Source: STRINGDB
MINAR2
Tdark
Novelty: 2.83783784
Score: 0.483
Data Source: STRINGDB
PTTG1IP
Tbio
Novelty: 0.10046933
Score: 0.473
Data Source: STRINGDB
CFL1
Tbio
Novelty: 0.00071544
Score: 0.473
Data Source: STRINGDB
THADA
Tbio
Novelty: 0.06983966
Score: 0.457
Data Source: STRINGDB
Publication Statistics
PubMed Score  28.23

PubMed score by year
PubTator Score  25.06

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer