Tdark DSCR4 Down syndrome critical region protein 4

Protein Summary

Description

The gene is found in a region of chromosome 21 that has been linked to the pathogenesis of Down syndrome. This gene is transcribed from a bi-directional promoter located in an endogenous retrovirus. [provided by RefSeq, Jan 2015]

Uniprot Accession IDs

• P56555
• Q4VB31

Gene Name

• DSCR4

Symbol

• DCRB
• DSCRB
• DCRB
• DSCRB

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.85
tissue	0.46
microRNA	0.42
tissue sample	0.42
cell line	0.36

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.97   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 39   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.97   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 39   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0