Tbio MTCP1 Protein p13 MTCP-1

Protein Summary

Description

Enhances the phosphorylation and activation of AKT1 and AKT2. This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the upstream 13 kDa protein that is a member of the TCL1 family. This protein may be involved in leukemogenesis. [provided by RefSeq, Mar 2009]

Uniprot Accession IDs

• P56278
• Q5HYP2
• p13MTCP1

Gene Name

• MTCP1

Ensembl ID

• ENST00000362018
• ENSP00000355058
• ENSG00000214827
• ENST00000369476
• ENSP00000358488

Symbol

• C6.1B
• p8MTCP1
• P13MTCP1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.86
cell type or tissue	0.76
small molecule perturbation	0.75
transcription factor perturbation	0.68
microRNA	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.64   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 57   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.64   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0