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Tbio
CMC4
Cx9C motif-containing protein 4

Protein Summary
Description
This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369479
  • ENSP00000358491
  • ENSG00000182712
  • ENST00000369484
  • ENSP00000358496

Symbol
  • C6.1B
  • MTCP1
  • MTCP1NB
  • p8
  • C6.1B
  • MTCP1
  • MTCP1B
  • MTCP1NB
  • p8MTCP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.87
cell type or tissue
0.8
histone modification site profile
0.73
tissue sample
0.67
gene perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.51   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 62   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.51   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (3)
1 – 3 of 3
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (2)
Mitochondrial protein import (R-HSA-1268020)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Mitochondrial protein import
Reactome
Protein localization
Name
Explore in Pharos
Explore in Source
Mitochondrial protein import
Protein localization
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (24)
1 – 10 of 24
HSPD1
Tbio
Novelty: 0.00018924
Score: 0.906
Data Source: STRINGDB
GFER
Tchem
Family: Enzyme
Novelty: 0.00338563
Score: 0.901
Data Source: STRINGDB
ATP5MC1
Tbio
Family: Enzyme
Novelty: 0.03538978
Score: 0.9
Data Source: STRINGDB
BCS1L
Tbio
Family: Enzyme
Novelty: 0.01764582
Score: 0.9
Data Source: STRINGDB
HSPA9
Tbio
Novelty: 0.00235171
Score: 0.9
Data Source: STRINGDB
SLC25A4
Tbio
Family: Transporter
Novelty: 0.01250865
Score: 0.9
Data Source: STRINGDB
ATP5F1A
Tbio
Family: Enzyme
Novelty: 0.01052213
Score: 0.9
Data Source: STRINGDB
TIMM22
Tbio
Family: Enzyme
Novelty: 0.12627933
Score: 0.9
Data Source: STRINGDB
CS
Tbio
Family: Enzyme
Novelty: 0.00154214
Score: 0.9
Data Source: STRINGDB
ATP5F1B
Tbio
Family: Enzyme
Novelty: 0.01053177
Score: 0.9
Data Source: STRINGDB
Publication Statistics
PubMed Score  12.51

PubMed score by year
PubTator Score  32.31

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer