MARS
Methionine--tRNA ligase, cytoplasmic
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
virus perturbation | 0.95 | ||
disease perturbation | 0.93 | ||
molecular function | 0.93 | ||
transcription factor binding site profile | 0.89 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytosolic tRNA aminoacylation | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Selenoamino acid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytosolic tRNA aminoacylation | ||||
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
Metabolism of proteins | ||||
Selenoamino acid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urate measurement | 6 | 5 | 7 | 5.2 | 98.6 | ||||
high density lipoprotein cholesterol measurement | 8 | 7 | 17 | 97.3 | |||||
triglyceride measurement | 7 | 6 | 13 | 2.7 | 89.8 | ||||
glomerular filtration rate | 3 | 2 | 3 | 89 | |||||
apolipoprotein A 1 measurement | 2 | 2 | 2 | 84.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urate measurement | 7 | 5.2 | 98.6 | ||||
high density lipoprotein cholesterol measurement | 17 | 97.3 | |||||
triglyceride measurement | 13 | 2.7 | 89.8 | ||||
glomerular filtration rate | 3 | 89 | |||||
apolipoprotein A 1 measurement | 2 | 84.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | methionyl-tRNA synthetase | VGNC:13216 | 452016 | |||||
Macaque | methionyl-tRNA synthetase | 714744 | ||||||
Mouse | MGI:1345633 | 216443 | ||||||
Rat | RGD:1305321 | 299851 | ||||||
Dog | methionyl-tRNA synthetase | VGNC:43027 | 474414 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | methionyl-tRNA synthetase | |||||
Macaque | methionyl-tRNA synthetase | |||||
Mouse | ||||||
Rat | ||||||
Dog | methionyl-tRNA synthetase | |||||
PMID | Year | Title |
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